I have thorn resistant (thicker, heavier) tubes in several bikes* & my bike trailer wheels ..
used a P/V 622-40 in my touring bikes wheels I went from SW Ireland , to NE Scotland with out a puncture..
over a 9 month period But I was in the smaller towns on the coast after Dublin..
* my 26" studded tire wheels, for example, I pump them up once for the season..
.....