after playing around with it a bit and searching on Lezyne's support site, it doesn't look like it

You create/upload the route to their portal (
http://lezyne.com/gpsroot) and then it syncs with the Ally app and then transfers to the GPS unit. There's a comment on their support site that the step to the phone is necessary because it optimizes the file for storage on the device:
DESIGN YOUR DESTINATION WITH LEZYNE NAVIGATION - Lezyne Blog