With my current tire and rim combination, it takes me less than 10 minutes to do the whole process with thru axles. I'm swapping tubes and not patching, though. I only patch when I get home or if I happen to flat again on the ride.
I have been riding with tubes containing sealant inside for months now. Since I haven't had any punctures and I wanted to save about 200g, yesterday I swapped out the front tube for regular ones. Woke up this morning to a flat front tire. Now the tubes with sealant is back in.