I've never heard anyone say they wish they hadn't gotten their Ortlieb panniers because they would have been better off with something else.
I have the stupidly named Ortlieb Bike Shopper panniers, with the 2.1 mounting system. They affix easily to my Tubus Fly Evo, and my Tubus Cargo Evo racks, and lift back off the bike with the pull of a handle.
I use them for commuting and general carry purposes. A typical commute means a change of clothes, laptop, tablet, and some other odds and ends. But I also use them when I take the kids to the park, to tote along lunch, or really anytime I need to carry something somewhere by bike. They're waterproof and durable.
(I dislike the name because it feels like it undersells their quality and value. When I think of a shopper I think of canvass re-use grocery bags and rattly wire baskets.)