Thank you for this thread! I had some very strange noises coming from the rear wheel that were driving me bonkers. It was a definite clicking sound when the wheel rolled, it happened twice per revolution and it changed with tire pressure and weight on the panniers. Eventually figured out it was an alignment plug in the rim that I fixed by filling the area with construction foam (thanks to another thread I cannot find again). Immediately after this fix, there was a lighter tinkling sound that seemed to change a bit under load. Found this thread and lued all the spokes at the rim, hub, and where they crossed. The noise is finally gone and I can enjoy a nice quiet bike ride again.

So much great information here