I fought numbness for 2-3 years. Went through an Avocet Touring and a fizik Aliante. Then a B17 Imperial -I got numb after 12-15 miles on that. The Selle Anatomica looks like it might be better than the B17 Imperial. The C17 looks like it may be better, too.

I tried out an ISM saddle, but I have forgotten which one. It put too much weight on my pubic rami, IMO, but it solved the numbness problem for rides up to 25 miles.

I've been riding a Selle SMP TRK for 3 years (2500 miles) with pretty good success, but recently I've been getting some numbness again. Since that has happened only after I've slogged for 10 miles against a 15+ mph headwind, maybe it's my poor cycling and not a saddle problem. Also, I'm 25 lbs lighter than 3 years ago, though, I may need new shorts. Once I change shorts, who knows what else will have to change?

I think the cure for numbness is to remove pressure from the perineum. If the TRK stops working, I think my next experiment might be a Rido (rido-cycling.com)....