xbartz- I got the email of your delated post. The description of chain rub in the combos your op states are not the result of a too tight/loose cable as they are opposing results WRT cable tension. Both might be the case if the trim functions weren't being used as they are intended to be. Make sure the shifter is all the way to the lowest ring click spot to check the inner ring and large rear cog combo. Accordingly make sure the shift lever has swung all the way inwards to unsure it's clicked to the furthest outward position when on the large ring and smallest rear cog. Of course the limit screws are assumed to be correct in that they are not limiting the cage's travel. For and rub between the lowest combo and the highest gear combo the trim functions are used.

BTW it's time to check your shift cables as they enter the lever's cable spool, just beyond where it's easy to see them if the casing was pulled back/out of the lever's seat. A fraying (and Shimano shifters are very well known for this wear point) will inhibit the fine movements of the cables, as in the trim functions. Andy