Originally Posted by
BillyD
The question IS ... which one is worse for your liver.
I'm an Ibu guy, my system laughs at acetaminophen.
Neither.
Ibuprofen is simply not liver-toxic because it isn't metabolized there. It can cause kidney damage in overdoses or in the face of serious dehydration. However, the main risk is intestinal bleeding. There is a theoretical risk of accelerated atherosclerosis in chronic high dose use. People with bleeding problems shouldn't take it.
Acetaminophen will wipe out the liver with overdose, but if you don't have pre-existing liver disease, take liver-toxic meds, and aren't stressing your liver with booze, it is completely safe at recommended doses.
End of story.