What kind of bike do you have? If it's a bike with a drop bar handlebar and old school non-aero brake levers it's NOT a good idea to flip it over to work on it. That's because the brake cables and brake cable housing can get bend and seriously lessen braking ability. I like to get the rear wheel of the ground with the bike upright. If you don't have a work-stand and you want to do this inside you can put a broom handle across the backs of two chairs and suspend the bike either by the saddle or by putting the handle through the frame if it's a men's frame bike. I have a low stool I sit on to work on the wheel. Another advantage of this is that the turning direction of the spokes doesn't change.

If you have a basement with exposed rafter it's simple to hang the bike up to work on it. My apartment has what looks like a cinder block ceiling. I drilled two holes into it and installed two swag lamp/flower pot hooks. The are about 30" apart inline with each other. I put a 1/4" cord on one hook and have a large loop in the opposite end. that loop fits over the nose or rear of my saddle. Another longer 1/4" cord is looped over the other hook. That cord has a loop at either end and those loops fit over either side of the handle bar on my bike. Thus the bicycle is suspended at a great working height and is pretty steady. The cord at the front ending one each side of the handlebar keeps the handlebar and wheel from flopping about.

I adjust the brake caliper until a pad is just rubbing on a part of the rim and then use that pad as a guide to adjust the trueness of the wheel.

I've even true a wheel by hanging the back end from a tree.

Good luck.

Cheers