Don't listen to that guy...you're not going to run into any issues.
12x100 front, and 12x142 rear has become the standard, and your Venge and the CLX's/Enve's all come with that standard. Now, if you had an older disc brake bike with the 135mm axel, then you'd be more limited.
PS. I wouldn't bother getting the Enve's. The CLX 50's are a phenomenal set of wheels.