those chainrings are pretty interesting, but they don't seem to have U.S. availability. Do you have a Shimano crank? The SRAM will obviously work, but I imagine there are a fairly large number of frames where they will not fit. And I'm not sure about front derailleurs either, 5mm is a lot.

Chain wear in lower gears should be better and in higher gears will be somewhat worse. Probably since nobody racks up many miles int he big chainring/small cassette, it will not be a big deal. Or it might make it back to the situation from the old days, when the small cogs in the back always wore out first. Nowadays, I always wear out the 17 tooth cog in the back and the smaller ones are okay