Like everything else in fitting your bike, it probably depends on where everything else is for your particular circumstance. Things such as reach to the handlebars and where the bottom bracket is underneath you to name a few. Possibly changing up the reach might give you more lee-way in seat height if that is an important need to you. And then there is the thing that everyone is different.

I've ridden road bikes and sometimes had and inch or tad more difference than my own bikes for quite a few miles and never felt anything other than I didn't quite like it.