Originally Posted by
noodle soup
Disc alignment is a simple one time fix, but proper cassette alignment isn't as easy to fix.
If cassette alignment is the concern, I'd try before buying. Derailleur adjustments aren't a huge hassle, but I wouldn't want to do it every time I wanted to swap wheels.
Is it ever the case that there's so much difference that a barrel adjuster can't accommodate the difference? Trying before buying makes sense, but obviously difficult if considering an online wheelset (eg. Lightbicycle), or getting an LBS to actually allow you to mount your cassette in order to try before buying?
If going to a one-size fits-all wheelset, I assume fair to say that swapping tires is typically more of a hassle than RD adjusting, especially if at least one of the tire sets is running tubeless (with sealant)?