For my daily commuter, I wanted to minimize flats to keep my commute time predictable. For convenience rather than for safety. Changing a flat in 40 degree drizzle in the dark isn't really much fun. At all.

I chose Schwalbe Marathon Plus in 35mm width. Great tire. It's not supple and it's not light weight. It has eliminated puncture flats from this bike over 3 years now. My only flat tire was from a failed valve.

But flats happen on my other bikes.