Had a heck of a battle with a Continental Grand Prix 4000s II tire just two Saturday's ago. First fight was getting it off of the rim it was already on, which was a wheel for a bike I scrapped last year due to nasty frame damage. Bike I wanted to put it on had experienced a tire failure, thankfully not while riding it, and I had no spare tires other than that. Thought I would never get that tire off!
But the worst was yet to come, I dare say it took me a half hour, and usage of two sets of tire levers, to force that crazy tire onto the rim of the bike wheel I needed it on. And then, of course Murphy's Law came into play, after all that trouble I managed to damage the inner tube and it now has a slow leak. Lesson learned, wire bead tires for me from now on.