As you say, everyone's different, so I'll add my positive review of my Selle Anatomica Titanico to counter the preceding negative reviews.
I can't compare to Brooks (apart from a very hard, uncomfortable knockoff on a Viscount bike) or other leather saddles, but the Titanico has been more suited to my anatomy than all the previous saddles I'd ever ridden on since the mid-1970s. I'm 135–150 lb., depending on season and fitness. Yes, I've had to turn the tensioning bolt a handful of times to reduce the hammock sag effect, but I've been on the original frame and leather for more than 7 years, and I ride 150–200 miles/week pretty much year round.
SA makes several different models aimed at different ranges of body weight and kinds of riding, so you need to pick the model best suited for you.