In Central Pennsylvania, most of the good gravel is either going up or going down a big hill. The 2.25" tires on my MTB definitely feel a lot more secure on downhills, and don't noticeably slow me on uphills. I was thinking about going with 44mm tires because it would be easier to get crank clearance and tire clearance. I'm using a lugged bb, so that's another constraint.
I'm currently using 38mm tires on my gravel bike, and I'm fairly happy with them, but I wouldn't mind more security on downhills. Then, to add to my analysis paralysis, Jan published this blog post.
https://www.renehersecycles.com/blog...eid=4c0ea92129
Yes, I posted this in gravel and had second thoughts and moved it.