How long and how far are you riding at a time? How often? What type riding are you doing, road, off road or x-games? What is your experience with cycling, recent or long past?

Usually pain is just your body getting used to a new experience. It can take some time. I and others have played around with swapping saddles and trying all sorts of different styles. I honestly believe that it's not so much that I found the right saddle as much as it was just that during that time span, my butt muscles got better.

There is also recumbent bicycles and trikes that bring another way of dealing with comfort.