I'm not a fan of KOP's. It has everyone emphasizing where the knee is in relation to the pedals and forgetting the other important things. If tube lengths and angles on a bike is perfectly fitted to the rider, then KOP's would probably seem like a great thing. But no production bike is going to fit everyone perfectly.

I used to have my seat pretty far back. That was when my bar height and seat height were close to the same. That's also when I had the most issues with wrist and shoulder pain. On my 60 cm 1991 Paramount and on my 56 cm 2020 Tarmac, my seat is pretty far forward and the handlebars are almost as low as they can go. There is a little setback in both seat posts, but not extreme. Less on the Tarmac.

I'm not saying it's right for you, but if you haven't tried it then you won't know. However don't do just the seat and not lower the bars. It's both together that helped me.