You probaby don't have enough tension in the spokes that are coming lose. Possibilities are
1. Their neighbors on the same side are tight so they're lose when the wheel is true. Make their neighbors loser so they can be tighter.
2. The whole wheel isn't tight enough for your weight. Download the app for that or use a Park tension meter. Shoot for 100 kgf average in the front, 110 kgf rear drive side, and whatever it takes to center the rear wheel on its non drive side.
3. You bent the rim and can't make it true with sufficient tension in that spoke. Loosen the spokes and bend it back or install a new rim.
4. You're not undoing the windup. Put a tape flag on the spoke or a sharpie dot and insure it ends up in the same position. With uniform tension you can use a representative spoke to see how far you have to back off - the first one after the valve hole, plus the next one in rear wheels.

You could also have cracked the rim and the lose spokes are slowly pulling out. Replace it.

You don't need any sort of locking goo or nipples given sufficient tension, even when you've lubricated the spoke threads and sockets which you should do so they're easier to turn later.

Properly tensioned your wheels will stay true until you bend a rim.