Big plus on wearing gloves! I just use leather work gloves when removing the cassette and especially when removing pedals. Yes, chain on the big ring helps from hand-intimately meeting-chainring teeth. I know I learned the hard way. Funny how experience is the teacher that gives the final exam first. Never had to visit the ER, but ripped flesh and scrapped knuckles sure slows down progress.
i’ve said to myself many times “wow, I’m glad I had gloves on”. I don’t recall many times I said, “I wish I didn’t have gloves on”.