This text concerns me. When you mean: "tighten the wheel", I assume you mean tighten the nut on the quick release skewer? Regardless, you do not tighten the quick release skewer with the nut - you tighten it by flipping the QR lever. Simply rotating the nut will not allow you exert enough force to properly tighten the skewer - not even close.

I volunteer at a high-volume bike co-op. A large percentage of the folks we work with have never properly learned how to use a QR. On newer bikes with 'lawyer lips', this is a minor inconvenience, as their wheels rock back and forth in the frame dropouts during the stresses of riding. On those older bikes without the lawyer taps, not knowing how to properly use a QR on the fork is truly life-threatening.

So if you had a frame with carbon dropouts, and the wheels were rocking back and forth due to inadequate QR clamping force, I could see how this could erode the dropouts and possibly destroy them.