Thanks again everybody. Thanks a lot for all the suggestions. By the afternoon of my 2nd day the pain had mostly subsided. I kept my knee warm for the remainder of the trip and moved my seat about 50 times till I found a perfect spot. I'm pretty experienced and should of knew better then to change my bike fit before a trip but lol it was just pedals. Big mistake. Any way I was able to complete my ride. 407 miles on the c&o and G.A.P and then back.I really appreciate all the advice.