Originally Posted by
Erik_A
The GRX 400 shifters (just like the latest versions of Tiagra) use 11 speed technology in the rear derailleurs, but just pull more cable to shift to ten speed (than Shimano's 11 speed shifters do). Therefore the 10 speed Tiagra and GRX 400 can use 11 speed rear derailleurs and vice versa. But it's not officially supported.
Yeah I’m actually a bit confused as to why an 810 RD wasn’t used instead. I’ve seen a build with 2x 11-40 using that RD.