In Ohio? That means some of the trains that normally ran might not run now with Covid, they cut back on schedule for long distance routes.

With a bike? Full size bike might be the deal breaker if you need roll on/roll off service if the bike racks are already booked. Folding bike could be one of your two allowable carry ons to avoid booking a space for full size bke.

Some stops do not sell tickets, have to buy on line.

Are your stops luggage stops or not?

You are asking lots of generic questions but answers depend on which stops you get on and off and whether or not they are luggage stops, whether or not they sell tickets at those stops, etc.

I used to use Amtrak a lot for touring, but have not used them for six years, thus I have no experience with roll on and roll off bike service.

I think you need to put together your list of questions with specific stops in mind and call Amtrak. They should be able to give you accurate answers for generic questions, however the phone operators probably are not up to speed on obscure information like folding bike policies.