A 5 hour ride is a substantial amount of time in the saddle with or without compliance. One really important factor is the distance travelled. A 5 hour ride at an average speed of 15 kph is going to feel very different than a 5 hour ride at a 25 kph average. When I ride at a relaxed pace I put a lot more weight on the saddle than when I ride fast. Bike setup also matters. If you ride as upright as possible your center of gravity shifts back to your saddle. The more of your weight on the saddle, the more likely it is that you will feel pain after a long ride