I definitely feel small changes, I'm really sensitive to the change but you can get used to it quickly.
I wouldn't heavily rely on online formulas. Use them as starting points and go from there. When I get a new bike or am making adjustments I go out for a ride just to see what works. I keep actual 4mm and 5mm keys in my pocket so I can easily adjust after a bit and see how things feel. When Im happy I ride home