I will sheepishly admit I added slime to a set of my tires for long distance rides.
The combination of Ambrosio rims and Continental tires makes it extremely difficult to remove the tire in case of need for repair.
I need 3-4 high quality tire levers to get the tire off, and then at least 4 to remount it. At the end I’m sweaty and exhausted.
Can’t imagine doing that on a ride, so I’m willing to take the trade offs.