I don't have any experience with 1X. I ride triples and friction shifters because they greatly reduce the amount of times you have to enact the shifter when you have to shift. That may not sound like much, but over an all day ride it adds up when you are going up and down and up and down. You can dump gears either way, lots of them. If I am using brifters, at the end of a long ride my right forearm is so tight that I cannot grip the handlebar or squeeze the brake lever. It becomes a safety issue.

Tomorrow I have to donate blood or platelets, as I do every 2-3 weeks. If it's platelets, I have to sit on the machine for over 2 hours squeezing a stress ball every 3-5 seconds. The squeezing movement, while not identical, is very similar to the movement of shifting a brifter. The same thing happens. After squeezing that ball for 2-3 hours every 3-5 seconds, I can no longer make a fist or grip anything. I have to sit in the car for some time before I can drive home. While I'm sitting in the car, I'm thinking, "This is why I don't care for brifters!"