It's an interesting concept, I've seen in various places recently - replacing the front 2X chainwheels with an internal hub 2X, wireless shifting with automatic shifting programmable. The downsides would be hard for the home mechanic to work on, maybe heavier? I'm interested in seeing how it works out.

With both Di2 and ETap, you can pretty much set shifting to be a 1X affair even with 2X cranks - the FD can shift automatically. The hub variation, from what I've read, eliminates any issue with shifting under pressure.