I'd say it depends on your weight and the weight of what you carry and the hills you'll hit.

I weigh 225 and ride a 2017 Domane SL6 disc, which I love. For a 4 day, lightly loaded (credit card style touring) ride from Venice FL to Jacksonville FL last January, all paved and very flat, I originally planned to ride the Domane with the 32mm tires. But, I weighed the extended saddle bag, small frame bag, bar bag loaded and 2 full water bottles, I felt I was coming too close to the overall weight limit. And I heard Florida friends stories of frequency of flatting on the many of the roads I'd be on. At my weight I'm very suspicious of a 24 spoke rear wheel.

So, I used my Jamis Renegade steel bike with 32 spoke rear, 35mm Schwalbe tires - a few lbs heaver, a bit higher rolling resistance. But the added weight was a small percentage of the overall loaded weight, almost no climbing on the route and I really hate fixing flats on the side of roads, Bonus - more braze-on options.

But, as a follow up: with about 9K miles on the Domane (after I returned from that January FL trip) I broke a spoke on the rear wheel. My experience has always been one spoke breaking may be just an aberration, had it fixed - and another broke a few hundred miles later. The second spoke break for me has always meant have the wheel rebuilt, bike shop said they go by the 10% rule - wait for the third spoke on a 24 spoke wheel.

A few hundred miles later, boink - another went, I had the wheel rebuilt and some heavier duty bladed spokes used. So far, so good.

The good news is the carbon rims didn't even wobble down one spoke and the disc brakes didn't even rub, but for most of my 4-day route I wouldn't have been near a bike shop and would have had to try out my fiberglass replacement spoke/string I carry and never have used!

If you are lighter, that 24 spoke rear wheel probably won't be an issue. If your route has meaningful climbs, on paved roads I wouldn't worry about trashing the carbon frame/finish unless you will be dragging the bike on the ground!

So, YMMV - but for me reliability over speed on multi-day tours.