My last multi-month tour I used the Selle Italia, leather over firm padding. I wore that out, now I'm using a Selle Anatomica. I haven't ridden multiple months on it yet, but won't hesitate to do so. It's pretty nice so far. It's colder in winter, if that's a concern, but cooler is generally a good idea. I use lined shorts, not padded. I've never been a fan of padded shorts or saddles. I get more skin issues with soft padding.