I have always liked the Rema patches and kits. My co-worker swears by the Park glueless patches so I have a kit on it's way. The benefit is that with a rubber cement, the first patch you do, you pierce the tube and the glue is good. Then you put the kit away and you may not get to use the glue again for a year or more. Then you get the next flat, think that you have things covered, only to find out that the glue has dried up. This is the situation that I'm trying to avoid.

So now, I have a spare tube, and the glueless patches coming and I'll take along the Tip Top kit until I get confidence with the glueless patches.

By the way, my personal (yes, thrifty is an art and science) thinking is that as long as the patches are not on top of one another, and the valve stem area is good, keep patching the tube.