I'm just the opposite. I feel better after a ride (my work commute is 25mi r/t), and I ride at ~19-20mph riding speed, even though I'm a 'senior citizen' at 63+. I found that I feel better after a vigorous ride 45+ years ago when I was in college! I feel that it helps burn the toxins out of my system! Oh, and it is not simply a 'runner's high' since the overall good feeling 'high' lasts for a day or two afterwards.
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'75 Fuji S-10S bought new, 52k+ miles and still going!
'84 Univega Gran Tourismo
'84 Univega Viva Sport
'86 Miyata 710
'90 Schwinn Woodlands
Unknown brand MTB of questionable lineage aka 'Mutt Trail Bike'
Plus or minus a few others from time-to-time