I've tried a few of the products that have been talked about. All seem to work to diff. degrees. I had a bout with a persistent sore that hung around when i stepped up mileage. I went to a generic combination of antibiotic creme and cortizone creme. I not only got rid of sore without cutting back on riding but was more comfortable without discoloring the chamois. Use the creme and not the gel. And you can forget the jokes about washing shorts...they are cleaned at least every 300 miles...hehe