The one time that really stands out in my memory for wheel lifting was riding up Burke mt in Vermont. When I stopped for a breather, it was very very challenging getting going again, you have to start horizontally and quickly on the narrow road get turned and pedaling while leaning forward big time.
I was on a mtb with 22/28 low gear. Unloaded, maybe a small pannier with a lunch and stuff.

found this blurb about it:

: Extreme
scenery: 4
traffic: 5
road: 3
The average grade of 12.7% for 3.3 miles makes this the steepest top 100 climb in the USA. BUT, those stats do not represent the true torture of this climb!! After turning onto the toll road for the last 2.5 miles it averages OVER 14% [I had 14.27%] to the top . That includes a “wall” about 1.2miles long at 22% followed by 16%”recovery” slopes. Burke is hands down the toughest pure climb that I’ve ever done. Having climbed Mt Washington and Ascutney(the previous day)several times, along with Equinox, Lincoln Gap East, Mt Evans Colorado, Galibier and Mt Ventoux France, and several other top 100 climbs, that should give u some context/credibility to my statement. Bring your A+ game for this climb.