Ask 100 people this question and you'll get 110 different answers. A saddle is a very personal choice. What works for me and my anatomy and position won't necessarily work for you.

I'm perhaps more sensitive to saddles than some others. I'm a big guy at 100 kg, which doesn't help and not all that flexible. I've tried: Fizik Aliante and Tempo, Selle Italia Novus and SLR Boost Endurance, Specialized Power Arc and Power Mirror, SMP Dynamic, Plus and Well Gel and and SQ Labs 612 both active and non active.

The Fiziks and SQ Labs were ~1 hr saddles for me, the SLR Boost, SMP Dynamic about 1:30-1:45 and the Specialized Power Mirror and Arc are 2-2.5 hour saddles. The Power Arc was the first saddle I rode were I could last over 2 hours but started to make me numb over time. The Power Mirror, while expensive, resolved that numbness problem and it's a touch more comfy vs. the Arc, just stupidly expensive. The Power Mirror is the only saddle I can ride indoors for more than an hour without dying to get off, but for me the Arc is close & I think part of my numbness issue with the Arc is the wrong width, as it tapers quite a bit more than some other saddles in spite of the quoted measurements being the same (i.e. a 155mm saddle in the Power Arc is not the same as a 155mm saddle in another saddle like the original Power).

I'm also going to try the Romin Mirror, as I believe the shape is a little more to my liking vs. the flatter Power.