Though they reek of vintage appeal, wingnuts are a poor way to mount a wheel. I have then on my recently built Torpado (have used them before and did not like them) but only temporarily. I will be swapping them out for a set of quick release Campy low flange hubs shortly (well, will build them now and install them in the Spring, after Mother Nature takes her deep white coat away). You might get away with wingnuts on the front wheel but you are taking a chance on the rear. Put another way, I totally agree with clubman, bad idea on the rear wheel.
Hand tight is definitely
NOT adequate...
I don't do wheelies anymore and would be worried about front wingnuts if I did...