I never had strong hands and now with arthritis coming on, wing nuts would be a nightmare. Half my bikes are fix gear with nutted rear hubs. I use peanut butter wrenches at home and either a 6" crescent or Pedros Trixie on the road. (I fit the Trixie through straps I sew under my tool bag and secure with Velcro. Two minute wheel flips and I lift the chain off with the lockring spanner, keeping my hands clean.)
Peanut butter wrench - the classic Campagnolo, VAR or TA 15mm wrench for crank bolts. Shaped perfectly for spreading peanut butter.