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...I ride all over town here in Sacramento on 700x25 Vittoria Rubino Pro tyres. There is plenty of glass and crap in the bike lanes on public streets here. Youi do have to stay alert to it, and dodge around the worst of it. In wetter conditions, I usually end up on a bicycle set up with 700x28 Ruffy Tuffy tyres, or the more recent 700x33 Jack Brown's. I think the latest iteration of the Jack Brown tyre is 700x25, but they are rated at lower pressures than I prefer.

There's no one right answer to this that fits everyone, and the oly way you'll figure out your personal preference is by experimentation. But if you weigh 150 pounds, and itsounds like you will be riding mostly paved surfaces, 700x28 is plenty wide enough, and 700x25 in a decent tyre like the Vittoria's will probably work OK for you. I weigh considerably more than that.