I've been working on a compromise to the fully MUSA bike - maximally US made, made in Europe if not available here, and then giving in on shifting which you really can't get made outside Asia. And then to make it more challenging it's a weight weenie gravel bike on a steel frame with US made steel.
Custom True Temper S3 frame
Enve AG25 rims on Industry Nine hubs
White Industries crank, BB and headset
AX Lightness seatpost and Berk Dila saddle
Leaving GRX derailleurs, brifters and brakes, SRAM chain, 3T cassette, PRO carbon bar, Ritchey carbon adventure fork, Rene Herse tires.
Total weight should be right around 17.5 lb - not bad for a steel gravel bike!
Some doubters on the forum ask why you would want to do this - I say why not? Support small businesses that are keeping the bike world interesting.