I second (or thirds, fourths, etc) everyone's thoughts above. Go carbon. I'm 260-280 lbs, I'm on a Pinarello dogma f8 with Flo cycling wheels. Only issues I have had was when i was downshifting and popped the chain on the inner cog, causing the derauiller to break some spokes. Since then, wheels have been trued and running great! Wheels are more important for the build than most frames. Flo used to have an option for "clydesdales" but I can't seem to find it again. That being said, I am now running their FLO 77 AS (full carbon) wheels for the past 6 months and have had no issues with them. Cheaper than Zipp, ENVE, Princeton Carbon works, etc (maybe not as sexy) but the price savings, I think, is more important than weight savings at our weight class. Me shaving a few hundred grams on the bike means nothing when I can lose a lot more than that from riding.