I've been on a Trek Emonda SL5 for about 10k miles, no issues. I did upgrade the wheelset to a (now defunct) ALTO wheelset. I've replaced two spokes over the course of three years, but I'm not complaining, probably my fault for letting them go without a retensioning. I oscillate between 285-305 and FTP is in the ballpark of 300.

Trek usually has a 275 limit on road bikes. My cousin is a former shop owner and would always say it's fine as long as you're around 300. I'd also note that a lot of the new Bontrager wheels have no weight limit.

Good luck!