I was a Speedplay evangelist until I realized I was using energy trying to keep my floppy ankles and feet stabilized, because of the unsprung float and narrow platform. Your experience may be different, I favor Time because of the low stack height (foot closer to center of the axle) and a float that pivots differently from Look and Shimano. But they're all great.

I started on toeclips and slotted cleats almost 50 years ago, so in my book any clipless pedal is a cinch. Back in the day we'd all reached down to loosen a strap to put a foot down and fallen over on the side that was still strapped in. I finally went clipless around 1996: Look Delta clones, anything I could get my hands on. The toestraps where hurting my feet. I can hardly keep my feet on flat pedals anymore.