Depends on how you hang the bike in the garage. Make sure you remove the pair of wheelsets before hanging. Brass nipples last longer than other material, as a general rule. Still, you want to keep the spoke tension to remain in good condition. Hanging with stress on the wheelset is not the best.

There are wheel covers that would be ok to use and then store for extra protection. I am assuming that you will be removing the wheels from the bike.

Also, depends how near the home is to the ocean.

Also, tri bikes have specific wheelsets and costly.