Originally Posted by
MoAlpha
Right. So you're just saying that if the time constant is higher, the CTL will be lower and vice versa, or am I missing something more subtle?
Too bad no one will fund good studies to validate and track the relevant biomarkers for these things.
I don't think you're missing anything subtle. CTL will differ, so (almost always) the rate of change in CTL will differ. But empirically, we're probably talking a couple of points one way or the other. I was just bringing it up because Terry says Friel advises keeping below 8 and Terry is seeing 9.
I think some people have done some work on trying to estimate individual decay rates but to be frank I've never closely read that stuff so I don't know how well it works. But I like the general big picture idea of it.