From my correspondence with Microshift, iirc, shifters marked Nexus or Nexus/Alfine will work correctly with Alfine SG-S500 & SG-S501. Those marked Alfine will work correctly with Alfine hubs later than SG-S501.

Correctly: 1 is 1 and 8 is 8.
With a different generation of Alfine: 1 is 8 and 8 is 1