The numbness may not be from pressure on any one part of your hands and wrist. In my particular case its the angle (extension) of the wrist on the bars that causes the numbness. So I need to keep my hands almost most straight.
I now use thick high density foam bar tape on my bars (BV EVA Road Bike Handlebar Tapes). I switched to Bull Horn bars cause I really don't get into the drops anymore. Also with the Bull bars I can use Bar-End brakes and they have an easy strong grab.
https://belgiumcycles.com/hand-numbness-tingling/
I used to ride with a Physical Therapist. He made a CMC to Wrist support that he wore under his padded gloves. He was a young guy who had done allot of Mountain Biking as a kid and suffered wrist pain and finger numbness when ridding. They looked similar to this...
off net