I don't have any really expensive or even modern bicycles. But what I do know is that having an extra Basic Wheel Set for your favorite ride is like having another bicycle ready to go...

I have gotten some really good deals on economical machine made wheel sets. When I get them I loosen everything up and re-set, re-true, re-tune the wheel. Most often these adjustments are minor. I you get an economical wheel set and can't do this yourself then figure in the cost of a local shop to do the same. Now days I would not use any wheel set right out of the box.