The best saddle tilt for a given rider? Start with the nose and back level. Ride it. There's a fair to middlin' chance that level will feel great to you. If not, adjust it nose-up or nose-down, depending on how your butt and naughty bits (and hands) feel, a very little bit. Try again. Rinse and repeat until you like the result. The vast majority of us will end up with the nose level or a very few degrees off of level.
It isn't complicated. It may be mildly annoying dialing it in, but it isn't complicated.
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"I'm in shape -- round is a shape." Andy Rooney